Inter Cellular Adhesion Molecule 1

ICAM-1 DC54

Zeaxanthin-Rich Extract from Superfood Lycium barbarum Selectively Modulates the Cellular Adhesion and MAPK Signaling in Melanoma versus Normal Skin Cells In Vitro

Zeaxanthin-Rich Extract from Superfood Lycium barbarum Selectively Modulates the Cellular Adhesion and MAPK Signaling in Melanoma versus Normal Skin Cells In Vitro

The priority for implementing bioactive nutraceuticals in antioxidant-related therapies is of nice significance for pores and skin homeostasis in benign or malignant illnesses. So as to elucidate some novel insights of <i>Lycium barbarum</i> (Goji berry) exercise on pores and skin cells, the current examine centered on its energetic compound zeaxanthin. By focusing on the stemness markers CD44 and CD105, with deep implications in pores and skin oxidative stress mechanisms, we revealed, for the primary time, selectivity in zeaxanthin exercise.

When utilized in vitro on BJ human fibroblast cell line versus the A375 malignant melanoma cells, regardless of the average cytotoxicity, the zeaxanthin-rich extracts <b>1</b> and <b>2</b> have been in a position to downregulate considerably the CD44 and CD105 membrane expression and extracellular secretion in A375, and to upregulate them in BJ cells. At mechanistic stage, the current examine is the primary to exhibit that the zeaxanthin-rich Goji extracts are in a position to affect selectively the mitogen-activated protein kinases (MAPK): ERK, JNK and p38 in regular BJ versus tumor-derived A375 pores and skin cells. These outcomes level out in the direction of the functions of zeaxanthin from <i>L. barbarum</i> as a cytoprotective agent in regular pores and skin and raises questions on its use as an antitumor prodrug alone or together with commonplace remedy.

Postoperative adhesions (PA) are fibrotic tissues which are the commonest driver of long-term morbidity after stomach and pelvic surgical procedure. The optimum drug or materials to stop adhesion formation has not but been found. Complete understanding of mobile and molecular mechanisms of adhesion course of stimulates the design of future anti-adhesive methods. Not too long ago, disruption of peritoneal mesothelial cells have been recommended because the ‘motor’ of PA formation, adopted by a cascade of occasions (coagulation, irritation, fibrinolysis) and inflow of assorted immune cells, in the end resulting in a fibrous exudate.

We confirmed that a wide range of immune cells have been recruited into adhesive peritoneal tissues in sufferers with small bowel obstruction attributable to PA. The interactions amongst varied varieties of immune cells contribute to PA improvement following peritoneal trauma. Our overview focuses on the particular position of various immune cells in mobile and humoral mechanisms underpinning adhesion improvement.

Lateral Microscope Allows the Direct Commentary of Mobile Interfaces and Quantification of Modifications in Cell Morphology throughout Adhesion

The flexibility to watch cell adhesion processes in real-time stays a grand problem in primary biology and medication. Towards this aim, we’ve developed a lateral optical microscope that enables direct commentary of cell-substrate interactions in real-time on any substrate-transparent, opaque, or coated-without requiring labels or specialised optical parts. We exhibit the usage of our lateral microscope by quantifying dynamic adjustments in cell morphology throughout the first 90 min of adhesion to numerous supplies.

Particularly, we decided the charges of change involved angle of HeLa, 3T3, HEK293, and MDA-MB-231 cells on 5 totally different substrates: glass, collagen-coated glass, Nylon, PTFE, and collagen-alginate hydrogels. We used these charges of change to match adhesion of various cell traces on every floor, and to rank the adhesion-promoting capacities of the 5 surfaces for every cell line. For HeLa, 3T3, and HEK293 cells, we noticed maximal charges of change involved angle (0.058 min-1) on collagen-coated glass substrates. All 5 cell traces exhibited minimal charges of change (0.006 min-1) on PTFE.

Lateral microscopy additionally revealed a novel morphology amongst MDA-MB-231 breast most cancers cells throughout preliminary adhesion, which we quantified utilizing measurements of adjustments in cell top. Our lateral microscope is not going to solely allow extra complete, quantitative research of cell adhesion to tell the event of biomaterials however will in the end help in advancing our understanding of many vital organic processes and discovering new behaviors associated to cell adhesion.

EpCAM has lengthy been often called a cell floor protein extremely expressed in carcinomas. It has since turn out to be one of many key most cancers biomarkers. Regardless of its excessive fame, its precise position in most cancers improvement continues to be controversial. Past a flurry of correlative research, which level both to a optimistic or a unfavorable hyperlink with tumour development, there was surprisingly few research on the precise mobile mechanisms of EpCAM and on their useful penalties. Clearly, EpCAM performs a number of vital roles, in cell proliferation in addition to in cell adhesion and migration. The 2 latter features, straight related for metastasis, are the main focus of this overview.

Zeaxanthin-Rich Extract from Superfood Lycium barbarum Selectively Modulates the Cellular Adhesion and MAPK Signaling in Melanoma versus Normal Skin Cells In Vitro

Alpha-Lipoic Acid Performs a Function in Endometriosis: New Proof on Inflammasome-Mediated Interleukin Manufacturing, Mobile Adhesion and Invasion

Endometriosis is an estrogen-linked gynecological illness outlined by the presence of endometrial tissue on extrauterine websites the place it varieties invasive lesions. Alterations in estrogen-mediated mobile signaling appears to have a necessary position within the pathogenesis of endometriosis. Increased estrogen receptor (ER)-β ranges and enhanced ER-β exercise have been detected in endometriotic tissues. It’s well-known that ER-β interacts with parts of the cytoplasmic inflammasome-3 (NALP-3), the NALP-Three activation will increase interleukin (IL)-1β and IL-18, enhancing mobile adhesion and proliferation.

In any other case, the inhibition of ER-β exercise suppresses the ectopic lesions development. The current examine goals to analyze the potential impact of α-lipoic acid (ALA) on NALP-Three and ER-β expression utilizing a western blot evaluation, NALP-3-induced cytokines manufacturing by ELISA, migration and invasion of immortalized epithelial (12Z) and stromal endometriotic cells (22B) utilizing a 3D tradition invasion assay, and matrix-metalloprotease (MMPs) exercise utilizing gelatin zymography.

CytoSelect™ 48-well Cell Adhesion Assay (ECM Array, Fluorometric)
CBA-071 48 assays
EUR 555

CytoSelect™ 48-well Cell Adhesion Assay (ECM Array, Fluorometric)
CBA-071-5 5 x 48 assays
EUR 2430

CytoSelect™ 48-well Cell Adhesion Assay (Collagen I, Colorimetric)
CBA-052 48 assays
EUR 370

CytoSelect™ 48-well Cell Adhesion Assay (Collagen I, Fluorometric)
CBA-053 48 assays
EUR 400

CytoSelect™ 48-well Cell Adhesion Assay (Collagen IV, Colorimetric)
CBA-060 48 assays
EUR 370

CytoSelect™ 48-well Cell Adhesion Assay (Collagen IV, Fluorometric)
CBA-061 48 assays
EUR 400

CytoSelect 48-well Cell Adhesion Assay (Laminin, Colorimetric)
CBA-056 48 assays
EUR 512.4
Description: Cell adhesion is a complex process involved in migration/invasion, embryogenesis, wound healing and tissue remodeling. Cells adhere to the extracellular matrix, forming complexes with cytoskeleton components that can affect cell motility, differentiation, proliferation, and survival. Our CytoSelect 48-Well Cell Adhesion Assays provide a fully quantitative method for the evaluation of cell adhesion. The 48-well plate is precoated with Laminin.

CytoSelect 48-well Cell Adhesion Assay (Laminin, Fluorometric)
CBA-057 48 assays
EUR 553.2
Description: Cell adhesion is a complex process involved in migration/invasion, embryogenesis, wound healing and tissue remodeling. Cells adhere to the extracellular matrix, forming complexes with cytoskeleton components that can affect cell motility, differentiation, proliferation, and survival. Our CytoSelect 48-Well Cell Adhesion Assays provide a fully quantitative method for the evaluation of cell adhesion. The 48-well plate is precoated with Laminin.

CytoSelect 48-well Cell Adhesion Assay (Fibrinogen, Colorimetric)
CBA-058 48 assays
EUR 512.4
Description: Cell adhesion is a complex process involved in migration/invasion, embryogenesis, wound healing and tissue remodeling. Cells adhere to the extracellular matrix, forming complexes with cytoskeleton components that can affect cell motility, differentiation, proliferation, and survival. Our CytoSelect 48-Well Cell Adhesion Assays provide a fully quantitative method for the evaluation of cell adhesion. The 48-well plate is precoated with Fibrinogen.

CytoSelect 48-well Cell Adhesion Assay (Fibrinogen, Fluorometric)
CBA-059 48 assays
EUR 553.2
Description: Cell adhesion is a complex process involved in migration/invasion, embryogenesis, wound healing and tissue remodeling. Cells adhere to the extracellular matrix, forming complexes with cytoskeleton components that can affect cell motility, differentiation, proliferation, and survival. Our CytoSelect 48-Well Cell Adhesion Assays provide a fully quantitative method for the evaluation of cell adhesion. The 48-well plate is precoated with Fibrinogen.

CytoSelect™ 48-Well Cell Contraction Assay Kit
CBA-5021 48 assays
EUR 575

CytoSelect Tumor-endothelium Adhesion Assay
CBA-215 100 assays
EUR 692.4
Description: Leukocyte or tumor cell interactions with vascular endothelium consist of a cascade of processes including the firm attachment of cells to endothelial cell adhesion molecules. The CytoSelect Tumor Endothelium Adhesion Assay provides a robust system for the quantitative determination of interactions between tumor cells and endothelium. Adherent cells can be easily quantified on a fluorescence plate reader.

CytoSelect™ 96-well Leukocyte-endothelium Adhesion Kit
CBA-210 100 assays
EUR 495

CytoSelect™ 96-well Cell Transformation Assay
CBA-130 96 assays
EUR 640

CytoSelect™ 96-well Cell Transformation Assay
CBA-130-5 5 x 96 assays
EUR 2695

CytoSelect 96-well Leukocyte-epithelium Adhesion Kit
CBA-211 100 assays
EUR 692.4
Description: Leukocyte or tumor cell interactions with vascular endothelium consist of a cascade of processes including the firm attachment of cells to endothelial cell adhesion molecules. The CytoSelect Leukocyte Epithelium Adhesion Assay provides a robust system for the quantitative determination of interactions between leukocytes and epithelium. Adherent cells can be easily quantified on a fluorescence plate reader.

CytoSelect™ 96-well Phagocytosis Assay (Red Blood Cell)
CBA-220 96 assays
EUR 540

CytoSelect 384-well Cell Transformation Assay, Fluorometric
CBA-145 384 assays
EUR 1208.4
Description: Our CytoSelect 384-Well Cell Transformation Assay uses a modified soft agar 3D matrix to support the formation of colonies by neoplastic cells. Quantitation of cell transformation is performed on a fluorescence plate reader.

CytoSelect 384-well Cell Transformation Assay, Fluorometric
CBA-145-5 5 x 384 assays
EUR 4681.2
Description: Our CytoSelect 384-Well Cell Transformation Assay uses a modified soft agar 3D matrix to support the formation of colonies by neoplastic cells. Quantitation of cell transformation is performed on a fluorescence plate reader.

CytoSelect™ 24-well Cell Migration Assay (8 μm), Colorimetric
CBA-100 12 assays
EUR 480

CytoSelect™ 24-well Cell Migration Assay (8 μm), Colorimetric
CBA-100-5 5 x 12 assays
EUR 2180

CytoSelect™ 24-well Cell Migration Assay (8 μm), Fluorometric
CBA-101 12 assays
EUR 480

CytoSelect™ 24-well Cell Migration Assay (8 μm), Fluorometric
CBA-101-5 5 x 12 assays
EUR 2180

CytoSelect™ 24-well Cell Migration Assay (5 μm), Fluorometric
CBA-102 12 assays
EUR 480

CytoSelect™ 24-well Cell Migration Assay (5 μm), Fluorometric
CBA-102-5 5 x 12 assays
EUR 2180

CytoSelect™ 24-well Cell Migration Assay (3 μm), Fluorometric
CBA-103 12 assays
EUR 480

CytoSelect™ 24-well Cell Migration Assay (3 μm), Fluorometric
CBA-103-5 5 x 12 assays
EUR 2180

CytoSelect™ 96-well Cell Migration Assay (3 μm), Fluorometric
CBA-104 96 assays
EUR 580

CytoSelect™ 96-well Cell Migration Assay (3 μm), Fluorometric
CBA-104-5 5 x 96 assays
EUR 2535

CytoSelect™ 96-well Cell Migration Assay (5 μm), Fluorometric
CBA-105 96 assays
EUR 580

CytoSelect™ 96-well Cell Migration Assay (5 μm), Fluorometric
CBA-105-5 5 x 96 assays
EUR 2535

CytoSelect™ 96-well Cell Migration Assay (8 μm), Fluorometric
CBA-106 96 assays
EUR 580

CytoSelect™ 96-well Cell Migration Assay (8 μm), Fluorometric
CBA-106-5 5 x 96 assays
EUR 2535

CytoSelect™ 24-well Cell Migration Assay (12 μm), Colorimetric
CBA-107 12 assays
EUR 480

CytoSelect™ 24-well Cell Migration Assay (12 μm), Fluorometric
CBA-108 12 assays
EUR 480

CytoSelect™ 24-well Wound Healing Assay
CBA-120 24 assays
EUR 595

CytoSelect™ 24-well Wound Healing Assay
CBA-120-5 5 x 24 assays
EUR 2465

CytoSelect™ 24-well Collagen Cell Invasion Assay, Fluorometric
CBA-111-COL 12 assays
EUR 535

CytoSelect™ 96-well Collagen Cell Invasion Assay, Fluorometric
CBA-112-COL 96 assays
EUR 705

CytoSelect™ 96-well Phagocytosis Assay (Zymosan)
CBA-224 96 assays
EUR 620

CytoSelect™ 96-well Phagocytosis Assay (Zymosan)
CBA-224-5 5 x 96 assays
EUR 2670

CytoSelect™ 24-well Cell Invasion Assay (Basement Membrane), Colorimetric
CBA-110 12 assays
EUR 535

CytoSelect™ 96-well Cell Invasion Assay (Basement Membrane), Fluorometric
CBA-112 96 assays
EUR 705

CytoSelect™ 24-Well Cell Contraction Assay Kit (Floating Matrix Model)
CBA-5020 24 assays
EUR 495

CytoSelect™ 96-Well Hematopoietic Colony Forming Cell Assay (96 assays)
CBA-320 96 assays
EUR 440

CytoSelect™ 24-well Cell Haptotaxis Assay (8 µm), FN-coated, Colorimetric
CBA-100-FN 12 assays
EUR 505

CytoSelect™ 24-well Cell Haptotaxis Assay (8 µm), FN-coated, Fluorometric
CBA-101-FN 12 assays
EUR 505

CytoSelect™ 24-well Cell Haptotaxis Assay (8 µm), COL-coated, Colorimetric
CBA-100-COL 12 assays
EUR 505

CytoSelect™ 24-well Cell Haptotaxis Assay (8 µm), COL-coated, Fluorometric
CBA-101-COL 12 assays
EUR 505

CytoSelect 24-well Laminin Cell Invasion Assay, Fluorometric
CBA-111-LN 12 assays
EUR 714
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 24-well plates on either a standard microplate reader or a fluorescence plate reader. Inserts are precoated on the top of the membrane with Laminin.

CytoSelect 96-well Laminin Cell Invasion Assay, Fluorometric
CBA-112-LN 96 assays
EUR 908.4
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect 96-Well Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 96-well plates on a fluorescence plate reader. Inserts are precoated on the top of the membrane with Laminin.

CytoSelect™ 24-Well Wound Healing Assay, Trial Size
CBA-120-T 6 assays
EUR 295

CytoSelect™ 96-Well Hematopoietic Colony Forming Cell Assay (5 x 96 assays)
CBA-320-5 5 x 96 assays
EUR 1885

CytoSelect™ 24-Well Cell Migration Assay (8 µm, Colorimetric Format), Trial Size
CBA-100-T 4 assays
EUR 240

CytoSelect™ 24-Well Cell Migration Assay (8 µm, Fluorometric Format), Trial Size
CBA-101-T 4 assays
EUR 240

CytoSelect™ 24-Well Cell Migration Assay (3 µm, Fluorometric Format), Trial Size
CBA-103-T 4 assays
EUR 240

CytoSelect™ 24-well Anoikis Assay (Colorimetric/Fluorometric)
CBA-080 24 assays
EUR 505

CytoSelect™ 96-well Anoikis Assay (Colorimetric/Fluorometric)
CBA-081 96 assays
EUR 525

CytoSelect™ 96-Well Cell Transformation Assay (Soft Agar Colony Formation), Trial Size
CBA-130-T 24 assays
EUR 320

CytoSelect™ 24-well Cell Migration and Invasion Assay (8 µm), Colorimetric, Combo Kit
CBA-100-C 2 x 12 assays
EUR 915

CytoSelect™ 24-well Cell Migration and Invasion Assay (8 µm), Colorimetric, Combo Kit
CBA-100-C-5 10 x 12 assays
EUR 3950

CytoSelect™ 24-well Cell Migration and Invasion Assay (8 µm), Fluorometric, Combo Kit
CBA-101-C 2 x 12 assays
EUR 915

CytoSelect™ 96-well Cell Migration and Invasion Assay (8 µm), Fluorometric, Combo Kit
CBA-106-C 2 x 96 assays
EUR 1080

CytoSelect™ MTT Cell Proliferation Assay
CBA-252 960 assays
EUR 320

CytoSelect™ 24-Well Cell Invasion Assay (Basement Membrane, Colorimetric Format), Trial Size
CBA-110-T 4 assays
EUR 265

CytoSelect™ 24-Well Cell Invasion Assay (Basement Membrane, Fluorometric Format), Trial Size
CBA-111-T 4 assays
EUR 265

CytoSelect 24-Well Cell Migration Assay (5 µm, Fluorometric Format), Trial Size
CBA-102-T 4 assays
EUR 358.8
Description: Chemotaxis describes the movement of cells toward or away from a chemical stimulus in their environment. Cell chemotaxis plays a pivotal role in the progression of cancer and other diseases. CytoSelect Cell Migration Assays are ideal for determining the chemotactic properties of cells. The 5 µm pore size is ideal for monocytes / macrophages.

CytoSelect™ 96-Well Phagocytosis Assay (E. coli, Colorimetric Format)
CBA-222 96 assays
EUR 595

CytoSelect™ 24-Well Cell Co-Culture System
CBA-160 24 assays
EUR 365

CytoSelect™ 24-Well Cell Co-Culture System
CBA-160-5 5 x 24 assays
EUR 1585

CytoSelect™ Cell Viability and Cytotoxicity Assay
CBA-240 96 assays
EUR 305

CytoSelect 96-Well Cell Transformation Assay (Cell Recovery Compatible, Fluorometric), Trial Size
CBA-140-T 24 assays
EUR 547.2
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis.

CytoSelect™ Cell Proliferation Assay Reagent (Colorimetric)
CBA-253 10 mL
EUR 320

CytoSelect™ 24-well Collagen Cell Invasion, Colorimetric
CBA-110-COL 12 assays
EUR 535

CytoSelect 96-Well Phagocytosis Assay(Zymosan Substrate), Trial Size
CBA-224-T 20 assays
EUR 463.2
Description: Phagocytosis can be assayed by measuring the engulfment of a cell "substrate". However, traditional assays require tedious cell counting under a microscope. Our CytoSelect 96-Well Phagocytosis Assay, Zymosan Substrate provides a more accurate, user-friendly, high-throughput alternative to the standard phagocytosis assay. The assay may be adapted for use with 24-well or 48-well plates.

CytoSelect™ 96-well In Vitro Tumor Sensitivity Assay (Soft Agar Colony Formation)
CBA-150 96 assays
EUR 670

CytoSelect™ 96-well In Vitro Tumor Sensitivity Assay (Soft Agar Colony Formation)
CBA-150-5 5 x 96 assays
EUR 2935

CytoSelect™ 24-well Cell Invasion (Basement Membrane), Fluorometric
CBA-111 12 assays
EUR 535

CytoSelect™ LDH Cytotoxicity Assay Kit
CBA-241 960 assays
EUR 320

CytoSelect™ Leukocyte Transmigration Assay
CBA-212 24 assays
EUR 670

CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Colorimetric
CBA-135 96 assays
EUR 715

CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Colorimetric
CBA-135-5 5 x 96 assays
EUR 3095

CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Fluorometric
CBA-140 96 assays
EUR 750

CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Fluorometric
CBA-140-5 5 x 96 assays
EUR 3215

CytoSelect 24-well Laminin Cell Invasion, Colorimetric
CBA-110-LN 12 assays
EUR 714
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 24-well plates on either a standard microplate reader or a fluorescence plate reader. Inserts are precoated on the top of the membrane with Laminin.

CytoSelect Cell Proliferation Assay Reagent (Fluorometric)
CBA-250 10 mL
EUR 490.8
Description: Cell Biolabs? CytoSelect Cell Proliferation Assay Reagent (Fluorometric) provides a fluorometric format for measuring and monitoring cell proliferation. Cells can be plated and then treated with compounds or agents that affect proliferation.  Cells are then incubated with the proliferation reagent.  Upon entering metabolically active live cells, the non-fluorescent proliferation reagent is converted into a bright red fluorescent form. An increase in cell proliferation is accompanied by increased fluorescent signal, while a decrease in cell proliferation (and signal) can indicate the toxic effects of compounds or suboptimal culture conditions.  The assay principles are basic and can be applied to most eukaryotic cell lines, including adherent and non-adherent cells and certain tissues.  This cell proliferation reagent can be used to detect proliferation in bacteria, yeast, fungi, protozoa as well as cultured mammalian and piscine cells. The kit contains sufficient reagents for the evaluation of 960 assays in ten 96-well plates or 192 assays in eight 24-well plates.

CytoSelect™ Tumor Transendothelial Migration Assay
CBA-216 24 assays
EUR 670

CytoSelect 96-Well In Vitro Tumor Sensitivity Assay (Soft Agar Colony Formation), Trial Size
CBA-150-T 24 assays
EUR 483.6
Description: Traditionally, the soft agar colony formation assay has been used to monitor anchorage-independent growth. Cells proliferate for 3-4 weeks in a semisolid culture medium, followed by tedious manual counting of colonies. Our CytoSelect 96-Well In Vitro Tumor Sensitivity Assay provides a stringent, anchorage-independent model for chemosenstivity testing and screening of potential anticancer drugs. After just 6-8 days, cell colonies are quantified using a standard colorimetric microplate reader.

CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric, Trial Size
CBA-135-T 24 assays
EUR 518.4
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis.

CytoSelect™ BrdU Cell Proliferation ELISA Kit
CBA-251 96 assays
EUR 455

CytoSelect Clonogenic Tumor Cell Isolation Kit (5 preps)
CBA-155 5 preps
EUR 957.6
Description: Many solid tumors contain heterogeneous populations of normal and cancerous cells. Separation of these cell populations is key to an accurate assessment of the true genotypic and phenotypic differences between normal and tumor cells. Our CytoSelect Clonogenic Tumor Cell Isolation Kit uses a proprietary semisolid agar medium to facilitate formation of colonies by cells from solid tumors. Colonies are grown in either a 6-well plate or a 35mm culture dish. These colonies are isolated away from single (i.e. normal) cells by size filtration. The viable cells from these colonies can be easily recovered for further analysis.

CytoSelect Proliferating Cell Nuclear Antigen (PCNA) ELISA Kit
CBA-254 96 assays
EUR 672
Description: Cell Biolabs? CytoSelect Proliferating Cell Nuclear Antigen (PCNA) ELISA Kit is an enzyme immunoassay developed for the detection and quantitation of PCNA from nuclear and whole cell extracts.  The kit detects PCNA from mouse, rat and human, and has a detection sensitivity limit of 12.5 ng/mLPCNA.  Each kit provides sufficient reagents to perform up to 96 assays including standard curve and unknown samples. 

CytoSelect Clonogenic Tumor Cell Isolation Kit (5 x 5 preps)
CBA-155-5 25 preps
EUR 3894
Description: Many solid tumors contain heterogeneous populations of normal and cancerous cells. Separation of these cell populations is key to an accurate assessment of the true genotypic and phenotypic differences between normal and tumor cells. Our CytoSelect Clonogenic Tumor Cell Isolation Kit uses a proprietary semisolid agar medium to facilitate formation of colonies by cells from solid tumors. Colonies are grown in either a 6-well plate or a 35mm culture dish. These colonies are isolated away from single (i.e. normal) cells by size filtration. The viable cells from these colonies can be easily recovered for further analysis.

CytoSelect IdU Competitive ELISA Kit
CBA-5100 96 assays
EUR 651.6

CytoSelect EdU Competitive ELISA Kit
CBA-5101 96 assays
EUR 651.6

CytoSelect BrdU Competitive ELISA Kit
CBA-5098 96 assays
EUR 651.6

Radius™ 48-Well Cell Migration Assay
CBA-5037 48 assays
EUR 445

Radius™ 48-Well Cell Migration Assay
CBA-5037-5 5 x 48 assays
EUR 1895

Radius™ 24-Well Cell Migration Assay
CBA-125 24 assays
EUR 425

Radius™ 24-Well Cell Migration Assay
CBA-125-5 5 x 24 assays
EUR 1820

Radius™ 96-Well Cell Migration Assay
CBA-126 96 assays
EUR 495

Radius™ 96-Well Cell Migration Assay
CBA-126-5 5 x 96 assays
EUR 2095

Radius™ 24-Well Cell Migration Assay, (Collagen I Coated)
CBA-125-COL 24 assays
EUR 520

Radius 384-Well Cell Migration Assay
CBA-127 384 assays
EUR 721.2
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap.

Radius 384-Well Cell Migration Assay
CBA-127-5 5 x 384 wells
EUR 2802
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap.

Radius 24-Well Cell Migration Assay, (Laminin Coated)
CBA-125-LN 24 assays
EUR 714
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap.

Radius 24-Well Cell Migration Assay, (Fibronectin Coated)
CBA-125-FN 24 assays
EUR 714
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap.

Radius 24-Well Cell Migration Assay, (ECM Array Coated)
CBA-125-ECM 24 wells
EUR 838.8
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap.

OxiSelect™ 96-Well Comet Assay Kit
STA-355 96 assays
EUR 350

OxiSelect™ 96-Well Comet Assay Kit
STA-355-5 5 x 96 assays
EUR 1480

OxiSelect™ Comet Assay Slides (3-Well)
STA-352 5 slides
EUR 155

OxiSelect™ Comet Assay Slides (3-Well)
STA-353 25 slides
EUR 295

OxiSelect™ Comet Assay Slides (3-Well)
STA-353-5 5 x 25 slides
EUR 1150

OxiSelect™ 96-Well Comet Assay Slide
STA-356 1 slide
EUR 125

OxiSelect™ 96-Well Comet Assay Slide
STA-356-5 5 slides
EUR 440

OxiSelect™ Comet Assay Kit (3-Well Slides)
STA-350 15 assays
EUR 265

OxiSelect™ Comet Assay Kit (3-Well Slides)
STA-351 75 assays
EUR 520

OxiSelect™ Comet Assay Kit (3-Well Slides)
STA-351-5 5 x 75 assays
EUR 2195

Cell Meterâ„¢ Cell Adhesion Assay Kit
23010-100Tests 100 Tests
EUR 372
Description: The Cell Meterâ„¢ Cell Adhesion Assay Kit is a fast and sensitive assay for measuring cell-cell or cell-surface adhesion for a variety of cell types.

96-well Cellular Senescence Assay (SA β-Gal Activity)
CBA-231 120 assays
EUR 560

96-well Cellular Senescence Assay (SA β-Gal Activity)
CBA-231-5 5 x 120 assays
EUR 2490

96-Well ROCK Activity Assay Kit
STA-416 96 assays
EUR 750

96-Well ROCK Activity Assay Kit
STA-416-5 5 x 96 assays
EUR 3225

Cell Adhesion Assay (ECM Array, Colorimetric)
KT-838 48 tests
EUR 656

96-well Checkpoint Kinase Activity Assay Kit
STA-414 96 assays
EUR 908.4
Description: Our 96-well Checkpoint Kinase Activity Assay Kit provides a non-isotopic, sensitive and specific method to monitor checkpoint kinase activity using its physiological substrate; it can also be used in screening checkpoint kinase inhibitors.

96-well Checkpoint Kinase Activity Assay Kit
STA-414-5 5 x 96 assays
EUR 3672
Description: Our 96-well Checkpoint Kinase Activity Assay Kit provides a non-isotopic, sensitive and specific method to monitor checkpoint kinase activity using its physiological substrate; it can also be used in screening checkpoint kinase inhibitors.

96-Well Cellular Senescence Assay Kit (SA-β-gal Activity, Fluorometric Format), Trial Size
CBA-231-T 24 assays
EUR 280

Cell Adhesion Molecule 1 (CADM1) Magnetic Luminex Assay Kit
LKU603327-96T 96T
EUR 966

Basal Cell Adhesion Molecule (BCAM) Magnetic Luminex Assay Kit
LKU603686-96T 96T
EUR 917.7

Neuronal Cell Adhesion Molecule (NRCAM) Magnetic Luminex Assay Kit
LKU601071-96T 96T
EUR 966

Epithelial Cell Adhesion Molecule (EPCAM) Magnetic Luminex Assay Kit
LKU605989-96T 96T
EUR 917.7

Endothelial Cell Adhesion Molecule (ESAM) Magnetic Luminex Assay Kit
LKU604819-96T 96T
EUR 966

Neural Cell Adhesion Molecule 2 (NCAM2) Magnetic Luminex Assay Kit
LKU601063-96T 96T
EUR 966

Vascular Cell Adhesion Molecule 1 (VCAM1) Magnetic Luminex Assay Kit
LKU606099-96T 96T
EUR 1117.8

Vascular Cell Adhesion Molecule 1 (VCAM1) Magnetic Luminex Assay Kit
LKU606106-96T 96T
EUR 944.2

Vascular Cell Adhesion Molecule 1 (VCAM1) Magnetic Luminex Assay Kit
LKU606170-96T 96T
EUR 770.5

Vascular Cell Adhesion Molecule 1 (VCAM1) Magnetic Luminex Assay Kit
LKU606172-96T 96T
EUR 770.5

Vascular Cell Adhesion Molecule 1 (VCAM1) Magnetic Luminex Assay Kit
LKU606177-96T 96T
EUR 944.2

Vascular Cell Adhesion Molecule 1 (VCAM1) Magnetic Luminex Assay Kit
LKU606180-96T 96T
EUR 1043.1

Vascular Cell Adhesion Molecule 1 (VCAM1) Magnetic Luminex Assay Kit
LKU606185-96T 96T
EUR 993.6

Homing Associated Cell Adhesion Molecule (HCAM) Magnetic Luminex Assay Kit
LKU603176-96T 96T
EUR 894.7

Homing Associated Cell Adhesion Molecule (HCAM) Magnetic Luminex Assay Kit
LKU603179-96T 96T
EUR 944.2

Homing Associated Cell Adhesion Molecule (HCAM) Magnetic Luminex Assay Kit
LKU603186-96T 96T
EUR 869.4

Activated Leukocyte Cell Adhesion Molecule (ALCAM) Magnetic Luminex Assay Kit
LKU605456-96T 96T
EUR 869.4

Platelet/Endothelial Cell Adhesion Molecule (PECAM1) Magnetic Luminex Assay Kit
LKU606420-96T 96T
EUR 869.4

Platelet/Endothelial Cell Adhesion Molecule (PECAM1) Magnetic Luminex Assay Kit
LKU606422-96T 96T
EUR 944.2

Platelet/Endothelial Cell Adhesion Molecule (PECAM1) Magnetic Luminex Assay Kit
LKU606424-96T 96T
EUR 894.7

Collagen-based Cell Contraction Assay
CBA-201 24 assays
EUR 420

Mucosal Addressin Cell Adhesion Molecule 1 (MAdCAM1) Magnetic Luminex Assay Kit
LKU604908-96T 96T
EUR 917.7

Mucosal Addressin Cell Adhesion Molecule 1 (MAdCAM1) Magnetic Luminex Assay Kit
LKU604909-96T 96T
EUR 944.2

Cell Adhesion Molecule With Homology To L1CAM (CHL1) Magnetic Luminex Assay Kit
LKU606765-96T 96T
EUR 1062.6

OxiSelect™ Cellular Antioxidant Assay Kit (Green Fluorescence)
STA-349 192 assays
EUR 475

OxiSelect™ Flavonoid Assay Kit
XAN-5077 200 assays
EUR 420

OxiSelect™ AOPP Assay Kit (200 assays)
STA-318 200 assays
EUR 565

L1-Cell Adhesion Molecule (L1CAM) Magnetic Luminex Assay Kit
LKU606766-96T 96T
EUR 869.4

L1-Cell Adhesion Molecule (L1CAM) Magnetic Luminex Assay Kit
LKU606767-96T 96T
EUR 894.7

L1-Cell Adhesion Molecule (L1CAM) Magnetic Luminex Assay Kit
LKU606768-96T 96T
EUR 944.2

StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible)
CBA-325 96 assays
EUR 1027.2
Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis.

StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible)
CBA-325-5 5 x 96 assays
EUR 4033.2
Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis.

OxiSelect™ ORAC Activity Assay Kit
STA-345 192 assays
EUR 515

OxiSelect™ ORAC Activity Assay Kit
STA-345-5 5 x 192 assays
EUR 2175

OxiSelect™ HORAC Activity Assay Kit
STA-346 192 assays
EUR 515

OxiSelect™ HORAC Activity Assay Kit
STA-346-5 5 x 192 assays
EUR 2175

OxiSelect™ Polyamine Oxidase Assay Kit
XPX-5107 100 assays
EUR 365

Carcinoembryonic Antigen Related Cell Adhesion Molecule 1 (CEACAM1) Magnetic Luminex Assay Kit
LKU602926-96T 96T
EUR 966

Carcinoembryonic Antigen Related Cell Adhesion Molecule 1 (CEACAM1) Magnetic Luminex Assay Kit
LKU602929-96T 96T
EUR 993.6

Carcinoembryonic Antigen Related Cell Adhesion Molecule 3 (CEACAM3) Magnetic Luminex Assay Kit
LKU602933-96T 96T
EUR 966

Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 (CEACAM6) Magnetic Luminex Assay Kit
LKU602938-96T 96T
EUR 966

Carcinoembryonic Antigen Related Cell Adhesion Molecule 7 (CEACAM7) Magnetic Luminex Assay Kit
LKU602942-96T 96T
EUR 966

Carcinoembryonic Antigen Related Cell Adhesion Molecule 8 (CEACAM8) Magnetic Luminex Assay Kit
LKU602944-96T 96T
EUR 966

OxiSelect™ Glutathione Reductase Assay Kit
STA-812 100 assays
EUR 345

OxiSelect™ Protein Carbonyl Fluorometric Assay
STA-307 100 assays
EUR 580

OxiSelect™ Ascorbic Acid Assay Kit (FRASC)
STA-860 200 assays
EUR 485

OxiSelect™ TBARS Assay Kit (MDA Quantitation)
STA-330 200 assays
EUR 580

ALA considerably reduces ER-β, NALP-Three protein expression/exercise and the secretion of IL-1β and IL-18 in each 12Z and 22B cells. ALA remedy reduces mobile adhesion and invasion through a decrease expression of adhesion molecules and MMPs actions. These outcomes present convincing proof that ALA would possibly inhibit endometriosis development.

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