sonic hedgehog pathway

Sonic Hedgehog
PR15000CF 25 ug
EUR 459.6
Sonic Hedgehog
MO15043 500 ug
EUR 615.6
Sonic Hedgehog/Shh
E21-100 10ug
EUR 225
Description: Recombinant Human Sonic Hedgehog is produced by our E.coli expression system and the target gene encoding Cys24-Gly197 is expressed.
Sonic Hedgehog/Shh
E21-H69 10ug
EUR 225
Description: Recombinant Mouse Sonic Hedgehog is produced by our E.coli expression system and the target gene encoding Cys25-Gly198 is expressed.
Sonic Hedgehog protein
30R-AS052 25 ug
EUR 312
Description: Purified recombinant Human Sonic Hedgehog protein
Sonic Hedgehog protein
30R-AS053A 25 ug
EUR 312
Description: Purified recombinant Human Sonic Hedgehog protein
Sonic Hedgehog protein
30R-2426 25 ug
EUR 357
Description: Purified recombinant Human Sonic Hedgehog protein
Sonic Hedgehog protein
30R-2432 25 ug
EUR 357
Description: Purified recombinant Mouse Sonic Hedgehog protein
Sonic hedgehog protein
30R-3329 50 ug
EUR 337
Description: Recombinant Human Sonic hedgehog protein
Sonic hedgehog protein
AP87355 1mg
EUR 2640
Sonic hedgehog protein
AP88117 1mg
EUR 2640
Sonic hedgehog protein
AP88393 1mg
EUR 2640
Sonic hedgehog protein
AP79208 1mg
EUR 2640
Sonic Hedgehog antibody
70R-7123 50 ug
EUR 467
Description: Rabbit polyclonal Sonic Hedgehog antibody
Gli Report Cell Line-NIH3T3(Hedgehog Pathway)
ABC-RC200D 1 vial Ask for price
Description: The Gli Reporter – NIH3T3 Cell Line is designed for monitoring the activity of the hedgehog signaling pathway. The Gli Reporter – NIH3T3 Cell Line contains the firefly luciferase gene under the control of Gli responsive elements stably integrated into NIH3T3 cells. Luciferase expression correlates with activation of the hedgehog signaling pathway.
Gli Reporter - NIH3T3 Cell line (Hedgehog Pathway)
60409 2 vials
EUR 2445
Description: The Gli Reporter - NIH3T3 Cell Line is designed for monitoring the activity of the hedgehog signaling pathway. The Gli Reporter - NIH3T3 Cell Line contains the firefly luciferase gene under the control of Gli responsive elements stably integrated into NIH3T3 cells. Luciferase expression correlates with activation of the hedgehog signaling pathway.
Gli Reporter - NIH3T3 Cell line (Hedgehog Pathway)
GWB-PS8936 500reactions Ask for price
Sonic Hedgehog Rabbit mAb
58571 100ul
EUR 339
Sonic Hedgehog Rabbit mAb
A12695-100ul 100 ul
EUR 492
Sonic Hedgehog Rabbit mAb
A12695-200ul 200 ul
EUR 685.2
Sonic Hedgehog Rabbit mAb
A12695-20ul 20 ul
EUR 265.2
Sonic Hedgehog Rabbit mAb
A12695-50ul 50 ul
EUR 344.4
Sonic Hedgehog Rabbit pAb
E2347501 100μl
EUR 225
Description: Available in various conjugation types.
Sonic Hedgehog Rabbit pAb
E2380722 100ul
EUR 225
Description: Available in various conjugation types.
Sonic Hedgehog Rabbit mAb
E2R25772 100ul
EUR 255
Description: Available in various conjugation types.
Sonic Hedgehog Rabbit mAb
E2R380722 100ul
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody
Sonic Hedgehog, C24II, Human
HY-P7407 50ug
EUR 583.2
Sonic Hedgehog, C25II, Mouse
HY-P7409 50ug
EUR 583.2
Sonic Hedgehog, C24IVI, Human
HY-P7408 10ug
EUR 280.8
Shh Antibody / Sonic Hedgehog
F53068-0.08ML 0.08 ml
EUR 140.25
Description: Sonic hedgehog binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO.
Shh Antibody / Sonic Hedgehog
F53068-0.4ML 0.4 ml
EUR 322.15
Description: Sonic hedgehog binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO.
Shh Antibody / Sonic Hedgehog
F53217-0.08ML 0.08 ml
EUR 140.25
Description: Sonic hedgehog intercellular signaling is essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO. [UniProt]
Shh Antibody / Sonic Hedgehog
F53217-0.4ML 0.4 ml
EUR 322.15
Description: Sonic hedgehog intercellular signaling is essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO. [UniProt]
Shh Antibody / Sonic Hedgehog
F53264-0.08ML 0.08 ml
EUR 140.25
Description: Sonic hedgehog is an intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior- posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity).
Shh Antibody / Sonic Hedgehog
F53264-0.4ML 0.4 ml
EUR 322.15
Description: Sonic hedgehog is an intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior- posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity).
Human Sonic Hedgehog Antibody
32994-05111 150 ug
EUR 313.2
Mouse Sonic Hedgehog Antibody
33142-05111 150 ug
EUR 215
Human Sonic Hedgehog Antibody
33215-05111 150 ug
EUR 215
Recombinant Rat Sonic Hedgehog
cyt-1099-100g 100µg
EUR 900
Recombinant Rat Sonic Hedgehog
cyt-1099-1mg 1mg
EUR 4200
Recombinant Rat Sonic Hedgehog
cyt-1099-50g 50µg
EUR 600
Sonic Hedgehog Blocking Peptide
33R-7837 100 ug
EUR 119
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of SHH antibody, catalog no. 70R-7123
Recombinant Human Sonic HedgeHog
7-01477 5µg Ask for price
Recombinant Human Sonic HedgeHog
7-01478 25µg Ask for price
Recombinant Human Sonic HedgeHog
7-01479 1mg Ask for price
Recombinant Mouse Sonic HedgeHog
7-01483 5µg Ask for price
Recombinant Mouse Sonic HedgeHog
7-01484 25µg Ask for price
Recombinant Mouse Sonic HedgeHog
7-01485 1mg Ask for price
Recombinant Mouse Sonic HedgeHog
cyt-597-1mg 1mg
EUR 2520
Recombinant Mouse Sonic HedgeHog
cyt-597-25g 25µg
EUR 145
Recombinant Mouse Sonic HedgeHog
cyt-597-5g 5µg
EUR 60
Recombinant Human Sonic HedgeHog
cyt-676-1mg 1mg
EUR 2500
Recombinant Human Sonic HedgeHog
cyt-676-25g 25µg
EUR 145
Recombinant Human Sonic HedgeHog
cyt-676-5g 5µg
EUR 60
Sonic Hedgehog Mouse Recombinant
rAP-0436 Inquiry Ask for price
Sonic HedgeHog Human Recombinant
rAP-0437 Inquiry Ask for price
Recombinant Murine Sonic Hedgehog
AP60489 100ug
EUR 837
Recombinant Murine Sonic Hedgehog
MEOPP-1906 5ug Ask for price
Sonic Hedgehog (Shh) Rabbit mAb
A12695 1000μL
EUR 91
Description: Recombinant fusion protein containing a sequence corresponding to amino acids 22-133 of mouse CD83 (NP_033986.1).
Sonic Hedgehog Recombinant Protein
91-073 0.05 mg
EUR 651.3
Description: Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic development. SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems, such as limbs and brain. SHH also plays an important role in adult, including the division of adult stem cells and the development of certain cancers and other diseases. Human SHH is expressed as a 45kDa precursor, and undergoes a series of processing during secretion. After the removal of the signal peptide, a protease within the C-terminal domain catalyzes the cleavage of SHH into a 20 kDa N-terminal signaling domain (SHH-N) and a 25 kDa C-terminal domain (SHH-C). SHH-N has the “all signaling” capability. SHH-N binds to the 12 pass transmembrane protein Patched (Ptc) on cell surface, which releases the repression of the activity of Smoothened (Smo), a G-protein coupled receptor, by Ptc.
Sonic Hedgehog Recombinant Protein
91-083 0.05 mg
EUR 714.3
Description: Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic development. SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems, such as limbs and brain. SHH also plays an important role in adult, including the division of adult stem cells and the development of certain cancers and other diseases. Human SHH is expressed as a 45kDa precursor, and undergoes a series of processing during secretion. After the removal of the signal peptide, a protease within the C-terminal domain catalyzes the cleavage of SHH into a 20 kDa N-terminal signaling domain (SHH-N) and a 25 kDa C-terminal domain (SHH-C). SHH-N has the “all signaling” capability. SHH-N binds to the 12 pass transmembrane protein Patched (Ptc) on cell surface, which releases the repression of the activity of Smoothened (Smo), a G-protein coupled receptor, by Ptc.
Sonic Hedgehog Recombinant Protein
92-281 0.05 mg
EUR 651.3
Description: Mouse Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic development. SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems, such as limbs and brain. SHH also plays an important role in adult, including the division of adult stem cells and the development of certain cancers and other diseases.Mouse Shh is synthesized as a 437 aa precursor that contains a 24 aa signal sequence and a 413 aa mature region. The mature region is autocatalytically processed into a nonglycosylated, 20 kDa, 174 aa N­terminal fragment (Shh­N), and a catalytic­processing,glycosylated, 34 kDa, 239 aa C­terminal fragment. The 20 kDa Shh­N fragment is the core of the active hedgehog molecule. Mouse Shh­N is 99%, 98%, and 100% aa identical to human, rat and gerbil Shh­N, respectively.
Sonic Hedgehog Recombinant Protein
92-284 0.05 mg
EUR 651.3
Description: Mouse Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic development. SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems, such as limbs and brain. SHH also plays an important role in adult, including the division of adult stem cells and the development of certain cancers and other diseases.Mouse Shh is synthesized as a 437 aa precursor that contains a 24 aa signal sequence and a 413 aa mature region. The mature region is autocatalytically processed into a nonglycosylated, 20 kDa, 174 aa N­terminal fragment (Shh­N), and a catalytic­processing,glycosylated, 34 kDa, 239 aa C­terminal fragment. The 20 kDa Shh­N fragment is the core of the active hedgehog molecule. Mouse Shh­N is 99%, 98%, and 100% aa identical to human, rat and gerbil Shh­N, respectively.
Sonic Hedgehog Recombinant Protein
96-689 0.05 mg
EUR 519
Description: Sonic hedgehog protein (SHH) is also known as HHG-1, which belongs to the hedgehog family. SHH is expressed in fetal intestine, liver, lung, and kidney and not expressed in adult tissues. Sonic hedgehog protein can be cleavage into sonic hedgehog protein N-product and sonic hedgehog protein C-product by autolysis. SHH binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of patterning events during development. The C-terminal domain displays an autoproteolysis activity and a cholesterol transferase activity. The N-product is the active species in both local and long-range signaling, whereas the C-product has no signaling activity.
Sonic Hedgehog Recombinant Protein
40-701 5 ug
EUR 311.1
Description: Members of the Hedgehog (Hh) family are highly conserved proteins that are widely represented throughout the animal kingdom. The three known mammalian Hh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh), are structurally related, and share a high degree of amino acid sequence identity (e.g. Shh and Ihh are 93% identical). The biologically active form of each Hh molecule is obtained by autocatalytic cleavage of their precursor proteins, and each corresponds to approximately one half of the N-terminal portion of the precursor molecule. Although Hh proteins have unique expression patterns and distinct biological roles within their respective regions of secretion, they use the same signaling pathway and can be substituted for one another in experimental systems. Recombinant Murine Sonic Hedgehog is a 20.0 kDa protein consisting of 176 amino acid residues, including an N-terminal Ile-Val-Ile sequence substituted for the naturally occurring, chemically modified Cys residue.
Human sonic hedgehog ELISA kit
EKC35630-48T 48T
EUR 597.24
Human sonic hedgehog ELISA kit
EKC35630-5x96T 5x96T
EUR 4052.7
Human sonic hedgehog ELISA kit
EKC35630-96T 96T
EUR 853.2
Human sonic hedgehog ELISA Kit
ELA-E14874h 96 Tests
EUR 988.8
Human sonic hedgehog ELISA kit
CSB-E12005h-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human sonic hedgehog in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Human sonic hedgehog ELISA kit
1-CSB-E12005h
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  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human sonic hedgehog in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
SHH (Sonic Hedgehog) IHC Antibody
IW-PA1072-1 -
EUR 285
Sonic Hedgehog (C24II) N-Terminus
PR15018 25 ug
EUR 553.2
Human Sonic Hedgehog (N-terminal)
hAP-0240 100ug
EUR 250
Human Sonic hedgehog GENLISA ELISA
KBH6203 1 x 96 wells
EUR 286
Sonic Hedgehog Protein (SHH) Antibody
20-abx007235
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  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
Sonic Hedgehog Protein (SHH) Antibody
abx015984-100ug 100 ug
EUR 493.2
Sonic Hedgehog Protein (SHH) Antibody
abx012072-100ul 100 ul
EUR 493.2
Sonic Hedgehog Protein (SHH) Antibody
20-abx000551
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  • 100 ul
  • 200 ul
Sonic Hedgehog Protein (SHH) Antibody
20-abx214912
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  • 100 ul
  • 50 ul
Sonic Hedgehog Protein (SHH) Antibody
20-abx214963
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  • 100 ul
  • 50 ul
Sonic Hedgehog Protein (SHH) Antibody
abx237847-100ug 100 ug
EUR 610.8
Sonic Hedgehog Protein (SHH) Antibody
abx012072-100g 100 µg Ask for price
Sonic Hedgehog Protein (SHH) Antibody
abx012072-10g 10 µg
EUR 362.5
Sonic Hedgehog Protein (SHH) Antibody
abx012072-200g 200 µg Ask for price

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